Publications

Books

          2013 Cambridge Press                   2020 Springer Nature

Toxicology-of-Carbon-Nanotubes     

 

Journal Articles

If you do not have personal or institutional access please request a reprint from jcbonner@ncsu.edu

Lison D, Ibouraadaten S, van den Brule S, Todea M, Vulpoi A, Turcu F, Zeimann C, Creutzenberg O, Bonner JC, Ameloot M, Bové H. Femtosecond pulsed laser microscopy: a new tool to assess the in vitro delivered dose of carbon nanotubes in cell culture experiments. Particle Fibre Toxicol. 18(1):9, 2021.

Sridharan S, Taylor-Just AJ, Bonner JC. Osteopontin expression by rat mesothelial cells exposed to carbon nanotubes in a chronic in vitro transformation assay as a means for assessing risk for mesothelioma. Toxicology In Vitro 73:105126, 2021.

Ihrie MD, Taylor-Just AJ, Duke KS, Shipkowski KA, Bonner JC. STAT6-dependent exacerbation of house dust mite-induced allergic airway remodeling by multi-walled carbon nanotubes. NanoImpact 22:100309, 2021.

Taylor-Just AJ, You DJ, Lee HY, Turcu F, Creutzenberg O, Ziemann C, Van den Brule, Lison D, Bonner JC. Acute and chronic pulmonary toxicity by carboxyl- and amine-functionalized multi-walled carbon nanotubes in mice is determined by purification method. Particle Fibre Toxicol. 17(1):60, 2020.

You DJ, Bonner JC. Susceptibility Factors in Chronic Lung Inflammatory Responses to Engineered Nanomaterials. Int J Mol Sci. 2020 Oct 3;21(19):E7310. doi: 10.3390/ijms21197310.

You DJ, Lee HY, Taylor-Just AJ, Linder KE, Bonner JC. Sex differences in the acute and subchronic lung inflammatory responses of mice to nickel nanoparticles. Nanotoxicology. 2020 Aug 19:1-24. doi: 10.1080/17435390.2020.1808105.

Ihrie MD, Taylor-Just AJ, Walker NJ, Stout MD, Gupta A, Richey JS, Hayden BK, Baker GL, Sparrow BR, Duke KS, Bonner JC. Inhalation exposure to multi-walled carbon nanotubes alters the pulmonary allergic response of mice to house dust mite allergen. Inhal Toxicol. 2019 Apr;31(5):192-202. doi: 10.1080/08958378.2019.

Duke KS, Thompson EA, Ihrie MD, Taylor-Just AJ, Ash EA, Shipkowski KA, Hall JR, Tokarz DA, Cesta MF, Hubbs AF, Porter DW, Sargent LM, Bonner JC. Role of p53 in the chronic pulmonary immune response to tangled or rod-like multi-walled carbon nanotubes. Nanotoxicology. 2018 Nov;12(9):975-991. doi: 10.1080/17435390.2018.1502830.

Ihrie MD, Bonner JC. The Toxicology of Engineered Nanomaterials in AsthmaCurr Environ Health Rep. 2018 Feb 13. doi: 10.1007/s40572-018-0181-4.

Duke KS, Bonner JC. Mechanisms of carbon nanotube-induced pulmonary fibrosis: a physicochemical characteristic perspectiveWiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Oct 6. doi: 10.1002/wnan.1498.

Duke KS, Taylor-Just AJ, Ihrie MD, Shipkowski KA, Thompson EA, Dandley EC, Parsons GN, Bonner JC. STAT1-depedent and -independent pulmonary allergic and fibrogenic responses in mice after exposure to tangled versus rod-like multi-walled carbon nanotubesPart Fibre Toxicol. 2017 Jul 17;14(1):26.

Hilton GM, Taylor AJ, Hussain S, Dandley EC, Griffith EH, Garantziotis S, Parsons GN, Bonner JC, Bereman MS. Mapping differential cellular protein response of mouse alveolar epithelial cells to multi-walled carbon nanotubes as a function of atomic layer deposition coating. Nanotoxicology. 2017 Mar 13:1-14. doi: 10.1080/17435390.2017.1299888. [Epub ahead of print]

Hussain S, Ji Z, Taylor AJ, DeGraff LM, George M, Tucker CJ, Chang CH, Li R, Bonner JC, Garantziotis S. Multi-walled carbon nanotube functionalization with high molecular weight hyaluronan significantly reduces pulmonary injury. ACS Nano. 2016 Aug 23;10(8):7675-88.

Dandley EC, Taylor AJ, Duke KS, Ihrie MD, Shipkowski KA, Parsons GN, Bonner JC. Atomic layer deposition coating of carbon nanotubes with zinc oxide causes acute phase immune responses in human monocytes in vitro and in mice after pulmonary exposure. Part Fibre Toxicol. 2016 Jun 8;13(1):29.

Clippinger AJ, Ahluwalia A, Allen D, Bonner JC, Casey W, Castranova V, David RM, Halappanavar S, Hotchkiss JA, Jarabek AM, Maier M, Polk W, Rothen-Rutishauser B, Sayes CM, Sayre P, Sharma M, Stone V. Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterialsArch Toxicol. 2016 Jul;90(7):1769-83.

Shipkowski KA, Taylor AJ, Thompson EA, Glista-Baker EE, Sayers BC, Messenger ZJ, Bauer RN, Jaspers I, Bonner JC. An Allergic Lung Microenvironment Suppresses Carbon Nanotube-Induced Inflammasome Activation via STAT6-Dependent Inhibition of Caspase-1. PLoS One. 2015 Jun 19;10(6):e0128888.

Thompson, E.A., Sayers, B.C., Glista-Baker, E.E., Shipkowski, K.A., Ihrie, M.D., Duke, K.S., Taylor, A.J., Bonner, J.C. STAT1 Attenuates Murine Allergen-Induced Airway Remodeling and Exacerbationi by Carbon Nanotubes.  Am J Respir Cell Mol Biol. 2015 Mar 25. [Epub ahead of print]

Hilton, G.M., Taylor, A.J., McClure, C.D., Parsons, G.N., Bonner, J.C., Bereman, M.S. Toxicoproteomic analysis of pulmonary carbon nanotube exposure using LC-MS/MS. Toxicology. 2015 Mar 2;329:80-7.

Taylor, A.J., McClure, C.D., Shipkowski, K.A., Thompson, E.A., Hussain, S., Garantziotis, S., Parsons, G.N., Bonner, J.C. (2014) Atomic layer deposition coating of carbon nanotubes with aluminum oxide alters pro-fibrogenic cytokine expression by human mononuclear phagocytes in vitro and reduces lung fibrosis in mice in vivo. PLoS One. Sep 12;9(9):e106870.

Thompson, E.A., B.C. Sayers, E.E. Glista-Baker, K.A. Shipkowski, A.J. Taylor, J.C. Bonner. (2014) Innate Immune Responses to Nanoparticle Exposure in the Lung. J. Environ. Immunol. Toxicol. 1(3):150-156.

Hussain, S., S. Sangtian, S.M. Anderson, R.J. Snyder, J.D. Marshburn, A.B. Rice, A.B., J.C. Bonner, S. Garantziotis. (2014) Inflammasome activation in airway epithelial cells after multi-walled carbon nanotube exposure mediates a profibrotic response in lung fibroblasts. Part. Fibre Toxicol. 11:28.

Glista-Baker, E.E., A.J. Taylor, B.C. Sayers, E.A. Thompson, J.C. Bonner. (2014) Nickel nanoparticles cause exaggerated lung and airway remodeling in mice lacking the T-box transcription factor, TBX21 (T-bet). Part. Fibre Toxicol. 11:7.

Walters, D.M., K.M. White, U. Patel, M.J.  Davis, R.M. Veluci-Marlow, S.R. Bhupanapadu Sunkesula, J.C. Bonner, J.R. Martin, W. Gladwell, S.R. Kleeberger. (2014) Genetic susceptibility to interstitial pulmonary fibrosis in mice induced by vanadium pentoxide (V2O5). FASEB J. 3:1098-112.

Sayers, B.C., A.J. Taylor, E.E. Glista-Baker, J.K. Shipley-Phillips, R.T. Dackor, M.L. Edin, F.B. Lih, K.B. Tomer, D.C. Zeldin, R. Langenbach, J.C. Bonner. (2013) Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes. Am. J. Respir. Cell Mol. Biol. 49(4):525-35.

Meyer, M., R.N. Bauer, B.D. Letang, L. Brighton, E.A. Thompson, R.C. Simmen, J. C. Bonner, I. Jaspers. (2013) Regulation and activity of secretory leukoprotease inhibitor (SLPI) is altered in smokers. Am. J. Physiol. Lung Cell Mol. Physiol. 306(3):L269-76.

Bonner, J.C., R.M. Silva, A.J. Taylor, J.M. Brown, S.C. Hilderbrand, V. Castranova, D. Porter, A. Elder, G. Oberdörster, J.R. Harkema, L.A. Bramble, T.J. Kavanagh, D. Botta, A. Nel, K.E. Pinkerton. (2013) Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ. Health Perspect. 121(6):676-82.

Xia, T., R.F. Hamilton, J.C. Bonner, E.D. Crandall, A. Elder, F. Fazlollahi, T.A. Girtsman, K. Kim, S. Mitra, S.A. Ntim, G. Orr, M. Tagmount, A.J. Taylor, D. Telesca, A. Tolic, C.D. Vulpe, A.J. Walker, X. Wang, F.A. Witzmann, N. Wu, Y. Xie, J.I. Zink, A. Nel, A. Holian. (2013) Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ. Health Perspect. 121(6):683-90.

Glista, E.E., A.J. Taylor, B.C. Sayers, E.A. Thompson, J.C. Bonner. (2012) Nickel nanoparticles synergistically enhance PDGF-induced expression of chemokines by rat pleural mesothelial cells via prolonged activation of MAP kinase signaling. Am. J. Respir. Cell Mol. Biol. 47(4):552-61.

Lee, J.K., B.C. Sayers, K.S. Chun, H.C. Lao, J.C. Bonner, R. Langenbach. (2012) Multi-walled carbon nanotubes induce COX-2 expression via a MAP kinase-dependent mechanism in cultured RAW264.7 macrophages. Part. Fibre Toxicol. 9(1):14.

Zhang, H., D.R. Newman, J.C. Bonner, P.L. Sannes. (2012) Over-expression of human endosulfatase-1 exacerbates cadmium-induced injury to transformed human lung cells in vitro. Toxicol. Appl. Pharmacol. 265(1):27-42.

Bonner, J.C. (2011) Carbon nanotubes as delivery systems for respiratory disease: do the dangers outweigh the potential benefits? Expert Rev Respir Med. 5(6):779-87.

Wang, X., T. Xia, S. Addo Ntim, Z. Ji, S. Lin, H. Meng, C.H. Chung, S. George, H. Zhang, M. Wang, N. Li, Y. Yang, V. Castranova, S. Mitra, J.C. Bonner, A.E. Nel (2011) Dispersal State of Multiwalled Carbon Nanotubes Elicits Profibrogenic Cellular Responses That Correlate with Fibrogenesis Biomarkers and Fibrosis in the Murine Lung. ACS Nano. 5(12):9772-87.

Mossman, B.T., M. Lippmann , T.W. Hesterberg, K.T. Kelsey, A. Barchowsky, J.C. Bonner (2011) Pulmonary endpoints (lung carcinomas and asbestosis) following inhalation exposure to asbestos. J. Toxicol. Environ. Health B Crit. Rev. 14(1-4):76-121.

Bonner, J.C. (2010) Mesenchymal cell survival in airway and interstitial lung fibrosis. Fibrogenesis and Tissue Repair. 3(1):15.

Bonner, J.C. (2010) Nanoparticles as a potential cause of pleural and interstitial lung disease. Proc. Am. Thorac. Soc. 7(2):138-41.

Cesta, M.F., J.P. Ryman-Rasmussen, D.G. Wallace, T. Masinde, G. Hurlburt, A.J. Taylor, and J.C. Bonner (2010) Bacterial Lipopolysaccharide Enhances PDGF Signaling and Pulmonary Fibrosis in Rats Exposed to Carbon Nanotubes. Am. J. Respir. Cell Mol. Biol. 43(2):142-151.

Turpin, E.A., A. Antao-Menezes, M.F. Cesta, J.B. Mangum, D.G. Wallace, E. Bermudez, and J.C. Bonner (2010) Respiratory syncytial virus infection reduces lung inflammation and fibrosis in mice exposed to vanadium pentoxide. Respir. Res. 11:20.

Ryman-Rasmussen, J.P., M.F. Cesta, A.R. Brody, J.K. Shipley-Phillips, J.I. Everitt, E.W. Tewksbury, O.R. Moss, B.A. Wong, D.E. Dodd, M.E. Andersen, and J.C. Bonner (2009) Inhaled carbon nanotubes reach the subpleural tissue in mice.  Nature Nanotechnol. 4(11):747-51.

Ryman-Rasmussen, J.P., E.W. Tewksbury, O.R. Moss, M.F. Cesta, B.A. Wong, and J.C. Bonner. (2009) Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in a murine model of allergic asthma. Am. J. Respir. Cell. Mol. Biol. 40:349-358.

Card, J.W., D.C. Zeldin, J.C. Bonner, and E.R. Nestmann. (2008) Pulmonary applications and toxicity of engineered nanoparticles. Am. J. Physiol. Lung Cell Mol. Physiol. 3:L400-11.

Antao-Menezes, A., E.A. Turpin, P.C. Bost, J.P. Ryman-Rasmussen, and J.C. Bonner. (2008) STAT-1 signaling in human lung fibroblasts is induced by vanadium pentoxide through an IFN-beta autocrine loop. J. Immunol. 180(6):4200-7.

Voltz, J.W., J.W. Card, M.A. Carey, L.M. Degraff, C.D. Ferguson, G.P. Flake, J.C. Bonner, K.S. Korach, and D.C. Zeldin. (2008) Male Sex Hormones Exacerbate Lung Function Impairment After Bleomycin-Induced Pulmonary Fibrosis. Am. J. Respir. Cell. Mol. Biol . 1:45-52.

Bonner, J.C. (2007) Lung fibrotic responses to particle exposure. Toxicol. Pathol. 35(1):148-53.

Ingram, J.I., A. Antao-Menezes, E.A. Turpin, D.G. Wallace, J.B. Mangum, L.J. Pluta, R.S. Thomas, and J.C. Bonner (2007) Genomic analysis of human lung fibroblasts exposed to vanadium pentoxide to identify candidate genes for occupational bronchitis. Respir. Res. 8:34.

Mangum, J.B., E.A. Turpin, A. Antao-Menezes, M.F. Cesta, E. Bermudez, and J.C. Bonner (2006) Single-walled carbon nanotube (SWCNT)-induced interstital fibrosis in the lungs of rats is associated with increased PDGF mRNA and the formation of unique carbon structures that bridge alveolar macrophages in situ. Particle & Fibre Toxicol. 3:15.

Ingram, J.I., A. Antao-Menezes, J.B. Mangum, O. Lyght, P.J. Lee, J.A. Elias, and J.C. Bonner. (2006) Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of Egr-1 and PDGF ligands in pulmonary fibroblasts. J. Immunol. 177:4141-4148.

Walters, D.M. J.L. Ingram, A.A. Menezes, A. Nyska, Y. Tani, S.R. Kleeberger, and J.C. Bonner. (2005) Susceptibility of STAT-1-deficient mice to pulmonary fibrogenesis. Am. J. Pathol. 167:1221-9.

Bonner, J. C. (2004) Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev. 15:255-273.